SpeakersandAbstracts

Speakers and Abstracts

We have brought together researchers who have the potential to take the lead in quantitative biology as next-generation leaders.
次世代のリーダーとして定量生物学を牽引していくポテンシャルを有する研究者が揃っています。大御所を並べただけではない、定量生物学の会ならではの講演者のラインナップになっております。

Session: Quantity - FORCE -

Date and Time: Jan. 9th 13:10-15:25

Otger Campàs ( University of California, Santa Barbara, USA )

油滴を利用して、生体組織の力学を"その場で"測る。

Quantifying tissue mechanics in vivo and in situ
abstract:
Selected refs: Campàs et al. Nat. Methods (2014); Campàs et al. BPJ (2012); Campàs et al. PNAS (2010)

Kaoru Sugimura ( Kyoto University, Japan )

ベイズ統計学をつかって、見えない力を見る。アクチン結合タンパク質の力生成能と力感知能に注目して、形態形成の力学制御の分子メカニズムに迫る。

Quantifying epithelial tissue morphogenesis: from F-actin regulation to cell kinematics and tissue stress
abstract:
Selected refs: Guirao et al. eLife, in press; Sugimura and Ishihara. Development (2013); Ishihara and Sugimura. J. Theor. Biol. (2012)

Emmanuel Farge ( Institut Curie, France )

原腸形成過程は進化的に広くみられるが、コアとなる誘導シグナルははっきりしていなかった。それがなんと機械的応力である可能性が示された。

From mesoderm mechanotransductive evolutionary origins to tumourogenic mechanical induction
abstract:
Selected refs: Fernández-Sánchez et al. Nature (2015); Brunet et al. Nat. Commun. (2013); Farge. Curr. Biol. (2003)

Session: Quantity - SYMMETRY I -

Date and Time: Jan. 10th 9:00-12:00

Noriko Hiroi ( Keio University, Japan )

Anisotropy shaped by and for the dynamic distribution of heat
abstract:
Selected refs: Sumiyoshi et al. Front Physiol. (2015); Hiroi et al. Front Physiol. (2014)

Nicolas D Plachta ( IMCB, Singapore )

マウス初期胚の対称性の破れに定量イメージングで迫る

Seeing how mammalian life starts: Quantitative imaging in live mouse embryos
abstract:
Selected refs: Samarage et al. Dev. Cell (2015); Fierro-González et al. Nat. Cell Biol. (2013); Plachta et al. Nat. Cell Biol. (2011)

Yusuke Maeda ( Kyushu University, Japan )

title: tba
abstract:
Selected refs: Fukuyama et al. Langmuir (2015); Maeda et al. PNAS (2012); Maeda et al. PRL (2011)

Zoher Gueroui ( École Normale Supérieure, France )

title:tba
abstract:
Selected refs: Hoffmann et al. Nat. Nanotech. (2013); Pinot et al. PNAS (2012).

Session: Quantity - SYMMETRY II -

Date and Time: Jan. 10th 13:30-15:45

Cliff Brangwynne ( Princeton University, USA )

Cliff Brangwynne博士は物理学の視点から細胞生物学に新しいコンセプトを導入し、近年、大きなインパクトを与えて続けている新進気鋭の研究者です。「相転移/phase transition」は、例えば水分子が沸点や融点をまたぐと固体、液体、気体と急激に状態を変化させるような物理学のコンセプトです。Brangwynne博士は、細胞内で核小体や生殖顆粒が形成・消滅する過程を、この相転移現象として理解できることを明らかにしています。

title: tba
abstract:
selected refs: Berry et al. PNAS (2015); Feric and Brangwynne. Nat. Cell Biol. (2013); Brangwynne et al. Science (2009)

Akatsuki Kimura ( National Insititute of Genetics, Japan )

title: tba
abstract:
Selected refs: Hara et al. Mol. Biol. Cell (2013); Kimura and Kimura. PNAS (2011); Kimura and Onami. J. Cell Biol. (2007)

Brian Stramer ( King's College London, UK )

細胞のミクロとマクロを定量的 in vivo イメージングでつなぐ：細胞内アクチン動態・張力から細胞の巨視的挙動へ

Intercellular forces orchestrate contact inhibition of locomotion
abstract:
Selected refs: Davis et al. Cell (2015); Davis et al. Development (2012); Stramer et al. J. Cell Biol. (2010)

Session: Quantity - INFORMATION -

Date and Time: Jan. 10th 16:00-19:00

Satoshi Sawai ( the University of Tokyo, Japan )

title: tba
abstract:
Selected refs: Nakajima et al. Nat. Commun. (2014); Taniguchi et al. PNAS (2013); Gregor et al. Science (2010)

Damon Clark ( Yale University, USA )

Dissecting neural circuits for motion estimation in Drosophila
abstract:
Selected refs: Fitzgerald and Clark. eLife (2015); Clark et al. Nat. Neurosci. (2014); Clark et al. Neuron (2011);

Yuki Tsukada ( Nagoya University, Japan )

定量と再構築から理解する感覚神経細胞の環境認識
Quantification and reconstruction of thermosensory neuronal processing in C. elegans
abstract:
Selected refs:

David Umulis ( Purdue University, USA )

勾配情報が作り出す発生メカニズム
Quantification and modeling of BMP signaling during zebrafish embryo development
abstract:
Selected refs: Pargett et al. PLoS Comp. Biol. (2014); Peluso et al. Dev. Cell (2011); Umulis et al. Dev. Cell (2010)

Session: Quantities and Beyond -

Date and Time: Jan. 11th 9:00-11:00

Naoki Irie( the University of Tokto, Japan )

胚発生と進化の法則性として近年支持された砂時計モデル。この法則性を生み出すメカニズムの有力候補がみえてきた。

Double bladed aspect of gene recruitment to morphological evolution.
abstract:
Selected refs: Wang et al. Nat. Genetics (2013); Irie and Kuratani. Nat. Commun. (2011)

Yuichi Wakamoto ( the University of Tokyo, Japan )

title: tba
abstract:
Selected refs: Wakamoto et al. Science (2013); Wakamoto et al. Evolution (2012); Tomita et al. Langmuir (2011)

Tetsuya J Kobayashi( the University of Tokyo, Japan )

「量」をつなぐ：情報から適応度まで

Linking quantities from information to fitness
abstract:
Selected refs: Kobayashi and Sughiyama. PRL (2015); Kobayashi. PRL (2011); Kobayashi. PRL (2010)

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Toyota Physical & Chemical Research Institute Workshop
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